WebIn some cases, health care professionals may use the trade name taxotere when referring to the generic drug name docetaxel. Drug type: Docetaxel is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. This medication is classified as a "plant alkaloid," a "taxane" and an "antimicrotubule agent." WebApr 11, 2024 · Poorly-water soluble drugs (BCS class II and IV) can be incorporated in dissolving MAPs via NPs-loading. ... Cisplatin (CISPt) is one of the most widely used agent for chemotherapies and plays an essential role in DNA-modifying routes for tumor growth blocking, by apoptosis-induction of the cancer cells. ...
List of Products Permitted by DCG(I) and considered as …
WebCisplatin is approved to be used alone or with other drugs to treat: Bladder cancer. It is used alone in patients with advanced cancer that cannot be treated with other therapies, such as surgery or radiation therapy. Ovarian cancer that has spread to other parts of the body. It is used with other drugs in patients who have already had surgery ... WebCisplatin, a class of platinum-containing anticancer drugs for the treatment of solid tumors, is a substrate of OCT2 and MATE1/MATE2-K. OCT2 is expressed in the basolateral … highfield qualifications ucas
BIOPHARMACEUTICS CLASSIFICATION SYSTEM-BASED …
WebJul 20, 2024 · 5-Fluorouracil (5FU) is a BCS class III drug with good aqueous solubility and poor permeability, which severely limits its transdermal permeation through the stratum … WebThe biopharmaceutics classification system (BCS)-based biowaiver approach is intended to reduce the need for in vivo bioequivalence studies, i.e., it can provide a surrogate for in vivo Web2. Biopharmaceutics classification of the drug substance . BCS-based biowaivers are applicable to drug products where the drug substance(s) exhibit high solubility and, either high permeability (BCS Class I) or low permeability (BCS Class III). A biowaiver is applicable when the drug substance(s) in test and reference products are identical. A highfield qualifications uk